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HCG (Human Chorionic Gonadotropin): Hormonal Support for Men and Women

What Is HCG?

HCG is a hormone naturally produced by the placenta during pregnancy. It mimics the action of luteinizing hormone (LH), a key signal in the endocrine system that regulates testosterone production in men and ovulation in women.

In clinical and performance contexts, HCG is used to:

• Stimulate natural testosterone production

• Preserve testicular size and function

• Support fertility

• Assist in hormone restoration post-anabolic steroid use or during testosterone replacement therapy (TRT)

How It Works (in Men)

In males, HCG:

• Binds to LH receptors in the testes (Leydig cells)

• Triggers endogenous testosterone production

• Helps maintain spermatogenesis (sperm production)

• Prevents or reverses testicular atrophy during exogenous testosterone use

Medical and Performance Uses

Typical Dosages (Men)

Note: IU = International Units. Always consult a professional for hormone use.

Administration

• Route: Subcutaneous or intramuscular injection

• Storage: Typically comes as a lyophilized (dry) powder and must be reconstituted with bacteriostatic water; must be refrigerated after mixing

Potential Side Effects

While HCG is generally well tolerated, possible side effects include:

• Estrogenic effects: Increased estradiol, gynecomastia (manage with aromatase inhibitors if needed)

• Water retention or bloating

• Mood swings or irritability

• Desensitization of LH receptors (if used excessively or for long periods)

• Injection site discomfort

HCG vs. Other Hormonal Agents

Summary

HCG is a versatile hormonal agent widely used to support testosterone production, preserve fertility, and prevent testicular shrinkage, especially during TRT or steroid cycles. When used properly and under supervision, it is a powerful tool in men’s hormonal health management.